Antipsychotic Trials in Schizophrenia The CATIE Project 1st Edition by Scott Stroup, Jeffrey Lieberman – Ebook PDF Instant Download/Delivery:9780521895330, 0521895332
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Product details:
ISBN 10: 0521895332
ISBN 13: 9780521895330
Author: T. Scott Stroup, Jeffrey A. Lieberman
Antipsychotic medications are a key treatment for schizophrenia and sales of antipsychotic drugs approach $20 billion per year, with fierce marketing between the makers of the drugs. The U.S. National Institute of Mental Health sponsored the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project to provide independent information about the comparative effectiveness of medications. CATIE was the largest, longest and most comprehensive study of schizophrenia to date. Conducted under rigorous double-blind conditions, Antipsychotic Trials in Schizophrenia presents the definitive archival results of this landmark study. The core of the book consists of chapters focused on specific outcomes that set the CATIE findings in a wider context. Also included are chapters on the design, statistical analyses and implications for researchers, clinicians and policy makers. Psychiatrists, psychiatric researchers, mental health policy makers and those work
Antipsychotic Trials in Schizophrenia The CATIE Project 1st Table of contents:
1. Study design and protocol development process
2. Statistical considerations
3. Effectiveness and efficacy: staying on treatment and symptom reduction
4. Cost-effectiveness and cost-benefit analysis
5. Psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study
6. Neurocognition
7. Vocational outcomes
8. Family outcomes
9. Extrapyramidal side effects
10. Metabolic side effects and risk of cardiovascular disease
11. Substance use in persons with schizophrenia: incidence, baseline correlates, and effects on outcome
12. Violence in schizophrenia: prevalence, correlates, and treatment effectiveness
13. Genetic investigations in the CATIE sample
14. Human subjects considerations
15. Population pharmacokinetics of antipsychotics
16. Implications for research design and study implementation
17. Conclusion and implications for practice and policy
Index
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Scott Stroup,jeffrey Lieberman,Antipsychotic

