Capillary Electrophoresis Mass Spectrometry CE MS Principles and Applications 1st Edition by Gerhardus de Jong ISBN 1498747388 9781498747387

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Product details:

ISBN 10: 1498747388

ISBN 13: 9781498747387

Author: Gerhardus de Jong

This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields.
Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.

Table of contents:

1. Detection in Capillary Electrophoresis – An Introduction

    

2. Electrospray Ionization Interface Development for Capillary Electrophoresis-Mass Spectrometry

    

3. Sheath Liquids in CE-MS: Role, Parameters, and Optimization

    

4. Recent Developments of Microchip Capillary Electrophoresis Coupled with Mass Spectrometry

    

5. On-line Electrophoretic, Electrochromatographic, and Chromatographic Sample Concentration in CE-MS

    

6. CE-MS in Drug Analysis and Bioanalysis

    

7. Intact Protein Analysis by Capillary Electrophoresis – Mass Spectrometry

    

8. CE-MS in Food Analysis and Foodomics

    

9. CE-MS in Forensic Sciences with Focus on Forensic Toxicology

    

10. CE-MS in Metabolomics

     

11. CE-MS for Clinical Proteomics and Metabolomics: Strategies and Applications

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Tags: Gerhardus de Jong, Capillary Electrophoresis, Mass Spectrometry CE MS, Principles and Applications