Drug Discovery handbook 1st Edition by Shayne Cox Gad ISBN 0471728772 9780471728771

Drug Discovery handbook 1st Edition by Shayne Cox Gad – Ebook PDF Instant Download/Delivery: 0471728772, 9780471728771

Full download Drug Discovery handbook 1st Edition after payment

Product details:

ISBN 10: 0471728772

ISBN 13: 9780471728771 

Author: Shayne Cox Gad 

The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs.

This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including:

• Genomics, proteomics, high-throughput screening, and systems biology
• Summaries of how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, and more
• Specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques

The thorough coverage and practical, scientifically valid problem-solving approach of Drug Discovery Handbook will serve as an invaluable aid in the complex task of developing new drugs. 

Table of contents:

1. Natural Products

2. Cancer Cell Proteomics Using Molecular Aptamers

3. Molecular Similarity Methods and QSAR Models as Tools for Virtual Screening

4. Systems Biology Applications in Drug Discovery

5. HighThroughput Flow Cytometry

6. Combining NMR Spectral Information with Associated Structural Features to Form Computationally Nonintensive Rugged and Objective Models

7. Using Microsoft Excel as a Laboratory Data Management Tool

8. Age of Regulation

9. Simultaneous Screening of Multiple Cell Lines Using the CellCard System

10. Protein Xray Crystallography in Drug Discovery

11. Biological and Chemistry Assays Available During Drug Discovery and Developability Assessment

12. Strategies and Methods in Monitoring and Targeting ProteinProtein Interactions

13. HighThroughput Screening Evolution of Technology and Methods

14. MetalEnhanced Fluorescence Application to HighThroughput Screening and Drug Discovery

15. Methods for the Design and Analysis of ReplicateExperiment Studies to Establish Assay Reproducibility and the Equivalence of Two Potency Assays

16. Coupled Luminescent Methods in Drug Discovery 3Min Assays for Cytotoxicity and Phosphatase Activity

17. Design and Pharmaceutical Applications of Prodrugs

18. GABA and Glutamate Receptor Ligands and Their Therapeutic Potential in CNS Disorders

19. Cardiac Sarcolemmal ATPSensitive Potassium Channel Antagonists Novel IschemiaSelective Antiarrhythmic Agents

20. Factors Influencing the Efficacy of MediatorSpecific AntiInflammatory Glucocorticoid and Anticoagulant Therapies for Sepsis

21. Combinatorial Chemistry in the Drug Discovery Process

22. Herbal Medicines and Animal Models of Gastrointestinal Diseases

23. Endocrine and Metabolic Agents

24. Respiratory Viruses

25. Strategies in the Design of Antiviral Drugs

26. Protein Kinase Inhibitors in Drug Discovery

27. RNABased Therapies

28. Novel Imaging Agents for Molecular MR Imaging of Cancer

29. Targets and Approches for Cancer Drug Discovery

People also search for:

drug discovery handbook
    
handbook of assay development in drug discovery
    
drug discovery examples
    
cost of drug discovery and development
    
drug discovery techniques
    
drug discovery explained

Tags: Shayne Cox Gad, Drug Discovery, Handbook