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Telomerase Composition Functions and Clinical Implications Composition Functions and Clinical Implications 1st Edition by Aiden N Gagnon ISBN 1617283398 9781617283390

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Telomerase Composition Functions and Clinical Implications Composition Functions and Clinical Implications 1st Edition Aiden N. Gagnon Digital Instant Download

Author(s): Aiden N. Gagnon
ISBN(s): 9781617283390, 1617283398
Edition: 1
File Details: PDF, 2.03 MB
Year: 2010
Language: english
SKU: EB-51357842 Category: Tag:

Telomerase Composition Functions and Clinical Implications Composition Functions and Clinical Implications 1st Edition by Aiden N. Gagnon – Ebook PDF Instant Download/Delivery: 1617283398, 9781617283390

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Product details:

ISBN 10: 1617283398

ISBN 13: 9781617283390 

Author: Aiden N. Gagnon 

Telomerase is a ribonucleoprotein enzyme that catalyses the cellular synthesis of telomeric DNA during cellular division, resulting in maintenance of telomere length and increased proliferative potential. Several studies suggest that the telomerase may play an important role in the diagnosis and prognosis of cancer because its expression strongly correlates with the potential tumour progression. Ninety percent of human cancers on different organs have shown high telomerasa activity. This book reviews research in the field of telomerase including functions of telomerase independent of its interaction with telomeres on gene expression and chromatin structure; histone deacetylase inhibition as an anticancer telomerase-targeting strategy and others.

Table of contents: 

  1. Telomerase beyond telomeres: new roles for an old enzyme / Gabriele Saretzki

  2. Telomerase and telomeric proteins: a life beyond telomeres / Ilaria Chiodi, Cristina Belgiovine, Chiara Mondello

  3. Histone deacetylase inhibition as an anticancer telomerase-targeting strategy / Ruman Rahman

  4. Telomerase role in pituitary adenomas / A. Ortiz-Plata

  5. Regulations of telomerase activity and WRN gene expression / Fumiaki Uchiumi, Yoshikazu Higami, Sei-ichi Tanuma

  6. Telomerase and telomere dynamics in cancer: clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama

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Tags: Aiden N Gagnon, Telomerase, Composition, Functions, Clinical Implications