Computational Methods for Protein Folding, Volume 120 (Advances in Chemical Physics) 1st Edition by Richard A. Friesner, Ilya Prigogine, Stuart A. Rice – Ebook PDF Instant Download/Delivery: 0471209554, 978-0471209553
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ISBN 10: 0471209554
ISBN 13: 978-0471209553
Author: Richard A. Friesner, Ilya Prigogine, Stuart A. Rice
Computational Methods for Protein Folding, Volume 120 (Advances in Chemical Physics) 1st Edition: Since the first attempts to model proteins on a computer began almost thirty years ago, our understanding of protein structure and dynamics has dramatically increased. Spectroscopic measurement techniques continue to improve in resolution and sensitivity, allowing a wealth of information to be obtained with regard to the kinetics of protein folding and unfolding, and complementing the detailed structural picture of the folded state. Concurrently, algorithms, software, and computational hardware have progressed to the point where both structural and kinetic problems may be studied with a fair degree of realism. Despite these advances, many major challenges remain in understanding protein folding at both the conceptual and practical levels.
Computational Methods for Protein Folding seeks to illuminate recent advances in computational modeling of protein folding in a way that will be useful to physicists, chemists, and chemical physicists. Covering a broad spectrum of computational methods and practices culled from a variety of research fields, the editors present a full range of models that, together, provide a thorough and current description of all aspects of protein folding. A valuable resource for both students and professionals in the field, the book will be of value both as a cutting-edge overview of existing information and as a catalyst for inspiring new studies.
Computational Methods for Protein Folding is the 120th volume in the acclaimed series Advances in Chemical Physics, a compilation of scholarly works dedicated to the dissemination of contemporary advances in chemical physics, edited by Nobel Prize-winner Ilya Prigogine.
Computational Methods for Protein Folding, Volume 120 (Advances in Chemical Physics) 1st Edition Table of contents:
Chapter 1. Statistical analysis of protein folding kinetics
Chapter 2. Insights into specific problems in protein folding using simple concepts
Chapter 3. Protein recognition by sequence-to-structure fitness: bridging efficiency and capacity of threading models
Chapter 4. A unified approach to the prediction of protein structure and function
Chapter 5. Knowledge-based prediction of protein tertiary structure
Chapter 6. Ab initio protein structure prediction using a size-dependent tertiary folding potential
Chapter 7. Deterministic global optimization and ab initio approaches for the structure prediction of polypeptides, dynamics of protein folding, and protein-protein interactions
Chapter 8. Detecting native protein folds among large decoy sets with the OPLS all-atom potential and the surface generalized Born solvent model
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