Atherosclerosis Risks Mechanisms and Therapies 1st Edition by Hong Wang,Cam Patterson ISBN 1118285913 9781118285916

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Product details:

ISBN 10: 1118285913

ISBN 13: 9781118285916 

Author: Hong Wang, Cam Patterson

Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics.

Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields.

Table of contents:

Section I: Risk Factors: Old and New

1 Lipoproteins
2 Role of Dysglycemia in Atherosclerosis
3 Glycation, Inflammation and RAGE
4 Inflammation
5 Homocysteine
6 Hypertension
7 Genetics of Atherosclerosis
8 Life Style

Section II: Cellular Mechanisms
9. Endothelial Cells
10. Vascular Smooth Muscle Cells
11. Fibroblasts
12. Monocytes and Macrophages
13. Lymphocytes
14. Stem Cells
15. Platelets
16. Mouse Models of Atherosclerosis

Section III: Molecular Mechanisms
17. Renin Angiotensin System
18. Caveolae and Caveolins
19. Lysosomal Derangements
20. C-Reactive Protein
21. Paraoxonases
22. Prostanoids and Atherogenesis
23. Extracellular Phospholipases
24. Apolipoprotein-B
25. HDL Receptor SR-BI
26. Cytokine Networks
27. ECM and Atherosclerosis

Section IV: Biochemical Mechanisms
28. Nitric Oxide
29. Heme Oxygenase-1
30. Reactive Oxygen Species
31. Hydrogen Sulfide
32. Methylation
33. MicroRNAs
34. Posttranslational Modifications
35. Kinases and Phosphatases
36. MMPs, ROS, and Mitophagy

Section V: Clinical Management
37. Preventive Therapies
38. Risk Stratification
39. Molecular Imaging
40. Pharmacological Therapy
41. Targeted Molecular Therapeutics
42. HDL Therapies
43. Stem Cell Therapeutics
44. Surgical Revascularization

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Tags: Hong Wang, Cam Patterson, Atherosclerosis Risks, Mechanisms and Therapies