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Biologically responsive Hybrid Biomaterials A Reference for Material Scientists and Bioengineers 1st Edition by Jabbari Esmaiel ISBN 9814295671 9789814295673

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Biologically responsive Hybrid Biomaterials A Reference for Material Scientists and Bioengineers 1st Edition Jabbari Esmaiel Digital Instant Download

Author(s): Jabbari Esmaiel
ISBN(s): 9789814295673, 9814295671
Edition: 1
File Details: PDF, 15.01 MB
Year: 2010
Language: english
SKU: EB-4638936 Category: Tag:

Biologically responsive Hybrid Biomaterials A Reference for Material Scientists and Bioengineers 1st Edition by Jabbari Esmaiel – Ebook PDF Instant Download/Delivery: 9814295671, 9789814295673

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Product details:

ISBN 10: 9814295671 

ISBN 13:9789814295673 

Author:  Jabbari Esmaiel 

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field.This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials.There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Table of contents:

Section 1. Synthesis, Characterization and Self-Assembly

  • Chapter 1. Bulk and Solution Properties of Peptide-Polymer Conjugates

  • Chapter 2. Polymer-Peptide Conjugate Networks: Formation, Swelling and Degradation

  • Chapter 3. Peptide Self-assembly: Biomaterials Design and Application

  • Chapter 4. Micropatterned Polymer Structures for Cell and Tissue Engineering

  • Chapter 5. Synthesis and in vitro/in vivo Response to Peptide-Polymer Conjugates

Section 2. Hybrid Biomaterials in Drug Delivery and Molecular Recognition

  • Chapter 6. Synthesis of Multi-epitopic Glycopeptide-based Cancer Vaccines

  • Chapter 7. Stimuli-sensitive Particles for Drug Delivery

  • Chapter 8. Design and Synthesis of Endosomolytic Conjugated Polyaspartamide for Cytosolic Drug Delivery

  • Chapter 9. Engineering of Cell-penetrating Peptide-conjugated Intracellular Delivery Systems

Section 3. Cell Responsive Biomaterials in Tissue Engineering

  • Chapter 10. Biomimetic Matrices for Integrin-mediated Cell Adhesion

  • Chapter 11. Engineering Artificial Stem Cell Niches

  • Chapter 12. Engineering Peptides in Hydrogels for Cartilage Tissue Regeneration

  • Chapter 13. Biomimetic Materials for Engineering of Neural Tissues

  • Chapter 14. Hybrid Biomaterials for Engineering Vascular Tissues

  • Chapter 15. Dynamic Cell Culture Methods for Functionalized Biomaterials

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Tags: Jabbari Esmaiel, Biologically Responsive, Hybrid Biomaterials, Material Scientists, Bioengineers, Reference