Biology of Serpins Methods in Enzymology Volume 499 1st Edition by James Whisstock, Phillip Bird ISBN 0123864720 9780123864727

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Product details:

ISBN 10: 0123864720

ISBN 13: 9780123864727

Author:  James Whisstock, Phillip Bird 

Biology of Serpins (Methods in Enzymology, Volume 499) 1st Edition: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.

 

Biology of Serpins (Methods in Enzymology, Volume 499) 1st Edition Table of contents:

• Chapter 1: Analysis of serpin secretion, misfolding, and surveillance in the endoplasmic reticulum
• Chapter 2: Serpin-enzyme receptors: LDL receptor-related protein 1
• Chapter 3: The role of autophagy in alpha-1-antitrypsin deficiency
• Chapter 4: Serpins and the complement system
• Chapter 5: Use of mouse models to study plasminogen activator inhibitor-1
• Chapter 6: Plasminogen activator inhibitor type 2
• Chapter 7: The SerpinB1 knockout mouse
• Chapter 8: Investigating maspin in breast cancer progression using mouse models
• Chapter 9: Hsp47 as a collagen-specific molecular chaperone
• Chapter 10: Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor
• Chapter 11: The Drosophila serpins
• Chapter 12: Modeling serpin conformational diseases in Drosophila melanogaster
• Chapter 13: Using Caenorhabditis elegans to study serpinopathies
• Chapter 14: Using C. elegans to identify the protease targets of serpins in vivo
• Chapter 15: Viral serpin therapeutics
• Chapter 16: Human SCCA serpins inhibit staphylococcal cysteine proteases
• Chapter 17: Plants and the study of serpin biology

 

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