Cancer and Stem Cells 1st Edition by Thomas Dittmar, Kurt S Zanker ISBN 161668044X 9781616680442

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Product details:

ISBN 10: 161668044X 

ISBN 13: 9781616680442

Author: Thomas Dittmar; Kurt S. Zanker

Today, cancer is the second most prevelant cause of death, after heart disease, in the industrialized world. Till now, and despite promising results in cancer research, the primary cause of death in cancer is still 1: the formation of metastases at distant organs sites, 2: the presence of cancer cells that are resistant to current cancer therapies (chemotherapy/radiation) and which cause cancer relapse. Within the past three years it became evident that also solid tumor tissues contain a kind of stem cells, so-called cancer cells. These cancer stem cells have been described as chemo-/radiation therapy resistant tumor initating cells. The purpose of this book is to summarize the latest findings about the role of stem cells in cancer.

Table of contents:

1. Cancer Stem Cells: A Definition

2. Mathematical Modeling of Stem Cells Related to Cancer

3. Where Do Cancer Stem Cells Come From?

4. Mismatch Repair Deficiencies and Origin of Cancer Stem Cells

5. Cancer Stem Cells in Hematological Malignancies

6. Stem Cells in Solid Tumors

7. Cancer Stem Cells and Metastasis

8. Exercise, Stem Cells, and Cancer

9. Human Adult Stem Cells as Targets for Cancer Stem Cells: Evolution, OCT-4 Gene, and Cell to Cell Communication

10. Targeting Cancer Stem Cells

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