Clinical Dilemmas in Non Alcoholic Fatty Liver Disease Clinical Dilemmas 1st Edition by Roger Williams, Simon D Taylor Robinson ISBN 1118924975 9781118924976

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Product details:

ISBN 10: 1118924975

ISBN 13: 9781118924976 

Author: Roger Williams, Simon D. Taylor-Robinson

Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease offers hepatologists practical, up-to-date and expert guidance on the most topical dilemmas, difficulties and areas of controversy/difficulty surrounding this ever-increasing area of liver disease they face in daily practice.

Roger Williams and Simon Taylor-Robinson, two of Europe’s leading hepatologists, have recruited leading figures from across the world to assist them, resulting in a truly international approach. Each chapter covers a specific area of difficulty, containing clear learning points and providing evidence-based expert guidance on the latest hot topics in clinical management such as:

• Is NAFLD different in absence of Metabolic Syndrome?
• Are the pros outweighed by the cons of obtaining a liver biopsy?
• Is progression to cirrhosis more likely in children with NAFLD?
• What are the dangers as well as the true benefits of bariatric surgery?
• How is it best to use antifibrotic agents in clinical practice?

Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease provides the answers to the questions and challenges that clinicians face every day in this area. It is essential reading for hepatologists of all levels and researchers in hepatology, as well as all those involved in the care of patients with NAFLD, including gastroenterologists, pathologists and specialist hepatology nurses.

Table of contents:

Part I: Nature of the condition

1 Non-alcoholic fatty liver disease: Hype or harm?
2 NAFLD: A worldwide problem
3 Is insulin resistance the principal cause of NAFLD?
4 Paediatric NAFLD: A distinct disease with the propensity for progressive fibrosis
5 Non-alcoholic fatty liver disease (NAFLD) as cause of cryptogenic cirrhosis
6 Is NAFLD different in absence of metabolic syndrome?
7 Occurrence of noncirrhotic HCC in NAFLD
8 Fibrosis progression: Putative mechanisms and molecular pathways
9 When is it NAFLD and when is it ALD?: Can the histologic evaluation of a liver biopsy guide the clinical evaluation?
10 Of men and microbes: Role of the intestinal microbiome in non-alcoholic fatty liver disease
11 Can genetic influence in non-alcoholic fatty liver disease be ignored?
12 Is there a mechanistic link between hepatic steatosis and cardiac rather than liver events?

Part III: Diagnosis and Scoring

13 How to best diagnose NAFLD/NASH?
14 The clinical utility of noninvasive blood tests and elastography
15 Are the guidelines—AASLD IASL EASL and BSG—of help in the management of patients with NAFLD?
16 Imaging methods for screening of hepatic steatosis
17 Are the advantages of obtaining a liver biopsy outweighed by the disadvantages?
18 Screening for NAFLD in high-risk populations

Part IV: Value of treatment measures

19 Defining the role of metabolic physician
20 Should physicians be prescribing or patients self-medicating with orlistat vitamin E vitamin D insulin sensitizers pentoxifylline or coffee?
21 Effects of treatment of NAFLD on the metabolic syndrome
22 What are the dangers as well as the true benefits of bariatric surgery?
23 Liver transplantation: What can it offer?

Part V: What does the future hold?

24 Molecular antagonists leptin or other hormones in supplementing environmental factors?
25 What is the role of antifibrotic therapies in the current and future management of NAFLD?
26 Developmental programming of non-alcoholic fatty liver disease

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Tags: Roger Williams, Simon D Taylor Robinson, Clinical Dilemmas, Non Alcoholic Fatty Liver Disease