Computational Protein Protein Interactions 1st Edition by Ruth Nussinov, Gideon Schreiber 1420070057 9781420070057

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Product details:

ISBN 10: 1420070057 

ISBN 13: 9781420070057

Author: Ruth Nussinov, Gideon Schreiber 

Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. The broad recognition of their involvement in all cellular processes has led to focused efforts to predict their functions from sequences, and if available, from their structures. An overview of current research directions, Computational Protein-Protein Interactions examines topics in the prediction of protein-protein interactions, including interference with protein-protein interactions and their design.

Computational Protein Protein Interactions 1st Table of contents: 

1. Basic Principles of Protein–Protein Interaction
2. Low-Resolution Recognition Factors Determine Major Characteristics of the Energy Landscape in Protein–Protein Interaction
3. The Molecular Architecture of Protein–Protein Binding Sites
4. Mapping Protein Function by Combinatorial Mutagenesis
5. The Association of Protein–Protein Complexes
6. Computational Simulations of Protein–Protein and Protein–Nucleic Acid Association
7. Computational Design of Protein–Protein Interactions
8. Protein–Protein Docking
9. Prediction of Protein Interaction Sites
10. Predicting Molecular Interactions in Structural Proteomics
11. Rearrangements and Expansion of the Domain Content in Proteins Frequently Increase the Protein Connectivity in the Protein–Protein Interaction Network
12. Intrinsically Disordered Proteins and Their Recognition Functions
13. Identification of Druggable Hot Spots on Proteins and in Protein–Protein Interfaces
14. Designing Protein–Protein Interaction Inhibitors

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Tags: Computational, Protein, Protein Interactions, Ruth Nussinov, Gideon Schreiber