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Cytolytic Lymphocytes and Complement Effectors of the Immune System Volume 2 First Edition by Eckhard R Podack ISBN 1351071297 9781351079747

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Cytolytic Lymphocytes and Complement Effectors of the Immune System Volume 2 First Edition Podack Digital Instant Download

Author(s): Podack, Eckhard R
ISBN(s): 9781351079747, 1351071297
Edition: First edition
File Details: PDF, 28.55 MB
Year: 2017
Language: english
SKU: EB-7161478 Categories: , Tags: ,

Cytolytic Lymphocytes and Complement Effectors of the Immune System Volume 2 First Edition by Eckhard R. Podack – Ebook PDF Instant Download/Delivery: 1351071297, 9781351079747

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Product details:

ISBN 10: 1351071297 

ISBN 13: 9781351079747

Author: Eckhard R. Podack

These volumes, Cytolytic Lymphocytes and Complement: Effectors of the Immune System, originate from the realization that pathways of recognition and killings of foreign targets follow similar routes in the humoral and cellular part of the immune system. In particular, the homology of immunoglobins with the T-cell-MHC-antigen receptor at the beginning of the recognition sequence and the homology of complement component C9 with lymphocyte perforin 1 (P1) as pore formers at the end of the effector sequence are striking examples. 

Table of contents:

Part II.B (58 pages)
Cytolytic Mechanism — Killer Lymphocytes

  1. Properties and Function of Cytolytic Lymphocyte Granules
    By Eckhard R. Podack

  2. Properties of Transmembrane Channels Induced by Cytolytic Lymphocytes
    By John Ding-E Young, Eckhard R. Podack, Carl F. Nathan, Hans Hengartner, Zanvil A. Cohn

  3. The Role of Nuclear Damage in Lysis of Target Cells by Cytotoxic T Lymphocytes
    By Richard C. Duke, J. John Cohen

Part II.C (74 pages)
Cytolytic Mechanism — Soluble Cytotoxic Factors Produced by Lymphocytes

  1. Production and Function of Lymphotoxin Secreted by Cytolytic T Cells
    By Donald Scott Schmid, Nancy H. Ruddle

  2. Tumor Necrosis Factor/Cachectin
    By Frederick C. Kull

  3. Natural Killer Cytotoxic Factor (Nkcf) as Mediator in the Lytic Pathway of Nk Cell Mediated Cytotoxicity
    By Benjamin Bonavida, Susan C. Wright

  4. Tumor Necrosis Factors
    By Ramani A. Aiyer, Bharat B. Aggarwal

Part III (74 pages)
Therapeutic Applications

  1. A Function for Nk Cells in Acute Bone Marrow Allograft Rejection
    By Gunther Dennert

  2. Cytolytic T Lymphocyte Clones in Anti-Viral Immunity: Effector Function in Vivo and Mechanism of Action
    By T. J. Braciale, A. E. Lukacher, М. T. Sweetser, V. L. Braciale

  3. Interleukin-2 Activated Cytotoxic Lymphocytes (Lak Cells) as Antigen Nonspecific Amplifiers of the Immune Response: General Characteristics and Considerations For Cancer Therapy
    By Elizabeth Ann Grimm

  4. The Contribution of Natural Killer and T-Cells to the Lymphokine-Activated Killer Cell Phenomenon
    By Joseph H. Phillips, Brett T. Gemlo, Warren W. Myers, Anthony A. Rayner, Lewis L. Lanier

  5. Targeting for T-Lymphocyte-Mediated Lysis by Hybrid Antibodies
    By Uwe D. Staerz, Leo Lefrancois, Michael J. Bevan

  6. Long-Term Growth and Expansion of Ril-2 Activated Nk- Cells for Cancer Therapy
    By Eckhard R. Podack, Kristin O. Penichet, Ben-Yao Lin, Jen Wei Chiao, Abraham Mittelman

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Tags: Eckhard R Podack, Cytolytic Lymphocytes, Complement, Effectors, Immune System, Volume 2