Cytoskeletal Mechanics Models and Measurements 1st Edition by Mohammad R K Mofrad, Roger Kamm ISBN 1139458108 9781139458108

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Product details:

ISBN 10: 1139458108

ISBN 13: 9781139458108 

Author: Mohammad R. K. Mofrad, Roger Kamm

This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is the hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.

Table of contents:

1. Introduction and the biological basis for cell mechanics

2. Experimental measurements of intracellular mechanics

3. The cytoskeleton as a soft glassy material

4. Continuum elastic or viscoelastic models for the cell

5. Multiphasic models of cell mechanics

6. Models of cytoskeletal mechanics based on tensegrity

7. Cells, gels and mechanics

8. Polymer-based models of cytoskeletal networks

9. Cell dynamics and the actin cytoskeleton

10. Active cellular motion: continuum theories and models

11. Summary

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Tags: Mohammad R K Mofrad, Roger Kamm, Cytoskeletal Mechanics, Models, Measurements