Diabetes and C Peptide Scientific and Clinical Aspects 1st Edition Anders Sima ISBN 1617793914 9781617793912

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Product details:

ISBN 10: 1617793914

ISBN 13: 9781617793912

Author:  Anders A. F. Sima 

Diabetes & C-Peptide: Scientific and Clinical Aspects 1st Edition: In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide’s physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.

 

Diabetes & C-Peptide: Scientific and Clinical Aspects 1st Edition Table of contents:

1. C-Peptide and Insulin: A Happy Marriage

2. Peptide Interactions of Proinsulin C-Peptide

3. The Effect of Combined C-Peptide and Zinc on Cellular Function

4. C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy

5. Role of C-Peptide in the Regulation of Microvascular Blood Flow

6. Is NO-eNOS a Target for C-Peptide Action and Its Protective Effects on Diabetic Nephropathy?

7. Renoprotective Effects of C-Peptide on Type 1 Diabetes

8. The Mechanisms Underlying the Effects of C-Peptide on Type 1 Diabetic Neuropathy

9. C-Peptide and Type 1 Diabetic Encephalopathy

10. C-Peptide: A New Molecule with Anti-Inflammatory Properties

11. C-Peptide: Connecting Diabetes with Macrovascular Complications

12. C-Peptide and Diabetic Neuropathy in Patients with Type 1 Diabetes

13. Proatherogenic Effects of C-Peptide

14. Conclusions and Future Outlook

 

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