Evolution after Gene Duplication 1st Edition by Katharina Dittmar, David Liberles ISBN 0470593822 9780470593820

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Product details:

ISBN 10: 0470593822

ISBN 13: 9780470593820 

Author: Katharina Dittmar, David Liberles

Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity.

Key Features:

• Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system)
• A complete post-genome treatment of the topic originally covered by Ohno’s 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways
• Taps the significant increase in multi-gene family data that has resulted from comparative genomics
• Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication

This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.

Table of contents:

Chapter 1: Understanding Gene Duplication Through Biochemistry and Population Genetics
Chapter 2: Functional Divergence of Duplicated Genes
Chapter 3: Duplicate Retention After Small- and Large-Scale Duplications
Chapter 4: Gene Dosage and Duplication
Chapter 5: Myths and Realities of Gene Duplication
Chapter 6: Evolution After and Before Gene Duplication
Chapter 7: Protein Products of Tandem Gene Duplication: A Structural View
Chapter 8: Statistical Methods for Detecting Functional Divergence of Gene Families
Chapter 9: Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework
Chapter 10: Reconciling Phylogenetic Trees
Chapter 11: On the Energy and Material Cost of Gene Duplication
Chapter 12: Fate of a Duplicate in a Network Context
Chapter 13: Evolutionary and Functional Aspects of Genetic Redundancy
Chapter 14: Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds
Chapter 15: Gene and Genome Duplications in Plants
Chapter 16: Whole Genome Duplications and the Radiation of Vertebrates

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Tags: Katharina Dittmar, David Liberles, Evolution, Gene, Duplication