G Protein Coupled Receptors in Health and Disease Part A 1st Edition by Ya Xiong Tao ISBN 0123747570 9780123747570

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Product details:

ISBN 10: 0123747570

ISBN 13: 9780123747570 

Author: Ya-Xiong Tao

G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field.

Table of contents: 

Chapter 1: Rhodopsin-Mediated Retinitis Pigmentosa
Chapter 2: Human Diseases Associated with GPR54 Mutations
Chapter 3: Diseases Associated with Growth Hormone-Releasing Hormone Receptor (GHRHR) Mutations
Chapter 4: The Melanocortin-1 Receptor Gene Polymorphism and Association with Human Skin Cancer
Chapter 5: The Molecular Basis of Adrenocorticotrophin Resistance Syndrome
Chapter 6: Mutations in Melanocortin-4 Receptor and Human Obesity

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Tags: Ya Xiong Tao, G Protein Coupled Receptors, Health, Disease, Part A