Handbook for Clinical Trials of Imaging and Image Guided Interventions 1st Edition by Nancy A Obuchowski,G Scott Gazelle ISBN 1118849752 9781118849750

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Product details:

ISBN 10: 1118849752

ISBN 13: 9781118849750 

Author: Nancy A. Obuchowski, G. Scott Gazelle

Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers.

The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis.

Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.

Table of contents:

CHAPTER 1: Imaging technology assessment
CHAPTER 2: Clinical trials of therapy
CHAPTER 3: Clinical trials of image-guided interventions including radiotherapy studies
CHAPTER 4: Imaging as a predictor of therapeutic response
CHAPTER 5: Screening trials and design
CHAPTER 6: Practicalities of running a clinical trial
CHAPTER 7: Statistical issues in study design
CHAPTER 8: Introduction to biostatistical methods
CHAPTER 9: Methods for studies of diagnostic tests
CHAPTER 10: Methods for quantitative imaging biomarker studies
CHAPTER 11: Introduction to cost-effectiveness analysis in clinical trials
Index

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Tags: Nancy A Obuchowski, G Scott Gazelle, Clinical Trials, Imaging, Image Guided, Interventions