Immunobiology of the Shark 1st Edition by Sylvia L Smith , Robert B Sim , Martin F Flajnik ISBN 0367378043 978-0367378042

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Product details: 

ISBN 10: 0367378043 

ISBN 13:978-0367378042 

Author: Sylvia L Smith , Robert B Sim , Martin F Flajnik

Immunity studies in sharks over the past three decades have produced some remarkable discoveries. If one message rings true, it is that alternative animal model systems, such as sharks and their relatives, have contributed very substantially to a better understanding of the development evolution of our own immune system.

Immunobiology of the Shark describes the cellular, genetic, and molecular specifics of immune systems in sharks. Diverse approaches were employed to study the immunobiology of the shark from basic microscopic observations to detailed genome annotation. The book also raises a series of fascinating questions, which can be addressed experimentally using today’s technology.

This book will be a valuable resource for mainstream immunologists, comparative immunologists, geneticists, ecologists, evolutionary biologists, and investigators engaged in shark research. The book also aims to illustrate the magnificence of these animals as model systems and underscores the importance of their study to further understand their complex, and often enigmatic, biology.

Table of contents: 

1.The Diversity and Natural History of Chondrichthyan Fishes
2. Athena and the Evolution of Adaptive Immunity
3. Shark Reproduction, Immune System Development and Maturation
4. Sites of Immune Cell Production in Elasmobranch Fishes: Lymphomyeloid Tissues and Organs
5. Elasmobranch Blood Cells
6. Leukocyte Function in Elasmobranch Species: Phagocytosis, Chemotaxis, and Cytotoxicity
7. Cytokines of Cartilaginous Fish
8. Shark Complement: Genes, Proteins and Function
9. MHC Molecules of Cartilaginous Fishes
10. Considering V(D)J Recombination in the Shark
11. Shark Immunoglobulin Light Chains
12. Shark T-Cell Receptors
13. The Shark-Family (Cartilaginous Fish) Immunogenome
14. In Vitro Culture of Elasmobranch Cells
15. Antimicrobial Molecules of Sharks and Other Elasmobranchs: A Review
16. Shark-Derived Immunomodulators

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Tags: Sylvia L Smith, Robert B Sim, Martin F Flajnik, Immunobiology, Shark 1st