MicroRNA Methods 1st Edition by John J Rossi ISBN 0080551394 9780123739179

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Product details:

ISBN 10: 0080551394

ISBN 13: 9780123739179 

Author: John J. Rossi

MicroRNAs (miRNA) are tiny bits of genetic material that were unknown nearly 10 years ago but now represent an exciting field of study in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA (mRNA) by literally cutting it in half, interfering with the normal function of specific messenger RNAs in gene expression.

This “expression” of genes that code for essential proteins is essentially what controls whether a cell turns into a liver, lung, or brain cell, for example. Understanding what activates this process – or stops it – is a key to understanding the biological process and builds a foundation for advances in medicine and other fields. This volume in Methods in Enzymology presents valuable methods for studying MicroRNA, with three sections covering identification of MicroRNAs and their targets; MicroRNA expression, maturation and functional analysis; and MicroRNAs and disease.

Table of contents:

Foreword
Introduction
Tools to Answer Cosmic Questions
Chapter 1 The First Telescope
Chapter 2 The Era of the Giants
Chapter 3 Radio Telescopes: Discovering the Invisible Universe
Chapter 4 Observing the Violent Universe: X-rays and Gamma Rays
Chapter 5 Hubble
Chapter 6 Peering into the Future 
Notes
For Further Reading
Works Consulted
Index
Picture Credits
About the Author

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Tags: John J Rossi, MicroRNA, Methods