(EBOOK PDF) Nanoneuroscience and Nanoneuropharmacology 1st Edition by Hari Shanker Sharma ISBN 0444534318 9780080962245 full chapters

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Product details:

ISBN 10: 0444534318

ISBN 13: 9780080962245

Author:  Hari Shanker Sharma 

Nanoneuroscience and Nanoneuropharmacology 1st Edition: This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

 

Nanoneuroscience and Nanoneuropharmacology 1st Edition Table of contents:

• Drug delivery to the brain using colloidal carriers

  • Introduction
  • The blood–brain barrier
  • Strategies to overcome BBB
  • Brain drug delivery strategies via colloid carriers
  • Conclusions
  • Acknowledgments

• Quantum dot nanotechnologies for neuroimaging

  • Introduction
  • Semiconductor quantum dots and their utility for neurobiological imaging
  • Specific labeling and imaging of dissociated neurons and glial cells
  • Efficacy of different antibody conjugation methods to quantum dots
  • Labeling reactive gliosis in retinal tissue sections
  • Acknowledgments

• Colloidal systems for CNS drug delivery

  • Introduction
  • Classification of colloidal carriers for CNS drug delivery
  • Assays for the assessment of the BBB crossing by colloidal systems
  • Parameters of colloidal systems involved in the interaction with biological systems
  • Surface modification of colloidal carriers for CNS drug delivery
  • Ability of the colloidal carriers to cross the BBB
  • Polymeric brain-targeted Np
  • Brain-targeted liposomes
  • Surface functionalization of the colloidal systems
  • Albumin Np

• Applications of nanotechnology in molecular imaging of the brain

  • Introduction
  • Molecular imaging modalities
  • MRI contrast agents
  • Targeting of iron oxide-based contrast agents
  • Molecular imaging of the brain
  • Conclusions and future perspectives
  • Acknowledgment

• Development of iron chelator–nanoparticle conjugates as potential therapeutic agents for Alzheimer disease

  • Introduction
  • Excess metal toxicity and amyloid-β aggregation
  • Metal chelation and nanoparticle delivery
  • Preparation and use of specific nanoparticle–chelator conjugates
  • Effects of chelator–nanoparticle conjugate on Aβ aggregates and cytotoxicity
  • How might these nanoparticle conjugates enter the brain
  • Conclusion
  • Acknowledgments

• Carbon nanotubes as substrates/scaffolds for neural cell growth

  • Introduction
  • Structure, properties, and functionalization of CNTs
  • CNTs as substrates/scaffolds for neuronal cell growth
  • CNTs as substrate for other neural cells
  • Concluding remarks
  • Acknowledgments

• Neuromodulation

  • Introduction
  • Deep brain stimulation — current status
  • DBS — emerging trends
  • Sensory neuroprostheses — current status
  • Sensory neuroprostheses — emerging trends
  • Nanotechniques to optimize the NEI
  • Sensory neuroprostheses and DBS — cross-fertilization

• Nanoparticles

  • Introduction
  • Nanoparticle transport into the CNS
  • Nanoparticles as sensors of brain cell function and toxicity
  • Some adverse effects of nanoparticles on the dysregulation of brain redox status
  • Summary
  • Acknowledgments

• Nanoparticles influence pathophysiology of spinal cord injury and repair

  • Introduction
  • Nanoparticles aggravate pathophysiology of spinal cord injury
  • Nanoparticles enhance drug delivery
  • Nanoparticles enhance therapeutic effects of drugs in the spinal cord
  • Nanoparticles enhance neuroprotection in SCI
  • Possible mechanisms of nanowired drugs-induced neuroprotection
  • General conclusion
  • Acknowledgments

• Solid lipid nanoparticles and microemulsions for drug delivery

  • Introduction
  • Solid lipid nanoparticles
  • Microemulsions
  • Solid lipid nanoparticles for brain tumors therapy
  • Brain tumors
  • Drug delivery systems — solid lipid nanoparticles
  • Solid lipid nanoparticles and brain tumors
  • New therapeutical strategies
  • Future perspectives and novel challenges
  • Conclusions

 

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Hari Shanker Sharma,Nanoneuroscience,Nanoneuropharmacology