Nucleic Acids in Chemistry and Biology 1st Edition by G Michael Blackburn, Michael J Gait, David Loakes, David Williams ISBN 0854046542 9780854046546

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Product details:

ISBN 10: 0854046542

ISBN 13: 9780854046546 

Author: G. Michael Blackburn, Michael J. Gait, David Loakes, David Williams

The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecularly based introduction to the structure and biological roles of DNA and RNA. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids. The text is supported by an extensive list of references, making it a definitive reference source. This authoritative book presents topics in an integrated manner and readable style. It is ideal for graduate and undergraduates students of chemistry and biochemistry, as well as new researchers to the field.

Table of contents:

Cover
Title
Copyright
Foreword
Preface
Acknowledgements
Contents
Contributors
Glossary
Chapter 1 Introduction and Overview
Chapter 2 DNA and RNA Structure
Chapter 3 Nucleosides and Nucleotides
Chapter 4 Synthesis of Oligonucleotides
Chapter 5 Nucleic Acids in Biotechnology
Chapter 6 Genes and Genomes
Chapter 7 RNA Structure and Function
Chapter 8 Covalent Interactions of Nucleic Acids with Small Molecules and Their Repair
Chapter 9 Reversible Small Molecule-Nucleic Acid Interactions
Chapter 10 Protein-Nucleic Acid Interactions
Chapter 11 Physical and Structural Techniques Applied to Nucleic Acids
Subject Index

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Tags: G Michael Blackburn, Michael J Gait, David Loakes, David Williams, Nucleic Acids, Chemistry, Biology