Pharmaceutical perspectives of nucleic acid based therapeutics 1st Edition by Ram I Mahato, Sung Wan Kim ISBN 041528385X 9780203300961

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Product details:

ISBN 10: 041528385X

ISBN 13: 9780203300961 

Author: Ram I. Mahato, Sung Wan Kim

Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by controlling gene regulation, transcription, translation and replication.

Table of contents:

1. Gene Expression

2. Modulation of Gene Expression

3. Biophysical Aspects of Nucleic Acids and Carriers

4. Intracellular Trafficking

5. Nucleic Acid Delivery Systems

6. Biodistribution and Pharmacokinetics

7. Clinical Applications of Gene Therapy

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Tags: Ram I Mahato, Sung Wan Kim, Pharmaceutical, Perspectives, Nucleic, Acid, Based, Therapeutics