(EBOOK PDF)Pharmaceutical Statistics Practical and Clinical Applications Fourth Edition Revised and Expanded Drugs and the Pharmaceutical Sciences by Sanford Bolton 9780824757014 0824757017 full chapters

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Product details:

• ISBN 10:0824757017 

• ISBN 13:9780824757014

• Author:Sanford Bolton 

The fourth edition of a bestselling text, this book covers the use of statistics in pharmaceutical research and clinical evaluation. It includes a disk with special prograns to aid in problem analysis. The coverage progresses from basic definitions and concepts, data graphics, and probability through ANOVA, factorial designs, and optimization techniques. The discussion and examples have been expanded to include GMPs, validation, and quality control, as well as procedures and analyses in bioequivalence studies. The text presents fresh material on concept conformity and release targets and describes linear regression and correlation, the analysis of variance, and crossover designs.
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Pharmaceutical Statistics Practical and Clinical Applications Fourth Edition Revised and Expanded Drugs and the Pharmaceutical Sciences Table of contents:

 Chapter 1: Basic Definitions and Concepts
Chapter 2: Data Graphics
Chapter 3: Introduction to Probability: The Binomial and Normal Probability Distributions
Chapter 4: Choosing Samples
Chapter 5: Statistical Inference: Estimation and Hypothesis Testing
Chapter 6: Sample Size and Power
Chapter 7: Linear Regression and Correlation
Chapter 8: Analysis of Variance
Chapter 9: Factorial Designs
Chapter 10: Transformations and Outliers
Chapter 11: Experimental Design in Clinical Trials
Chapter 12: Quality Control
Chapter 13: Validation
Chapter 14: Computer-Intensive Methods
Chapter 15: Nonparametric Methods
Chapter 16: Optimization Techniques and Screening Designs
Glossary
Appendix I: Some Properties of the Variance
Appendix II: Comparison of Slopes and Testing of Linearity: Determination of Relative Potency
Appendix III: Multiple Regression
Appendix IV: Tables
Appendix V: Outlier Tests and Chemical Assays
Appendix VI: Should a Single Unexplained Failing Assay be Reason to Reject a Batch?
Appendix VII: When is it Appropriate to Average and its Relationship to the Barr Decision
Appendix VIII: Excel Workbooks and SAS Programs
Appendix IX: An Alternative Solution to the Distribution of the Individual Bioequivalence Metric∗
Appendix X: Some Statistical Considerations and AlternateDesigns and Considerations for Bioequivalen
Answers to Exercises
Back Cover

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