Pharmacology and Vitreoretinal Surgery Developments in Ophthalmology Vol 44 1st Edition by Arnd Gandorfer ISBN 3805590296 9783805590297

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Product details:

ISBN 10: 3805590296 

ISBN 13: 9783805590297

Author:  Arnd Gandorfer 

Since the advent of pars plana vitrectomy, immense technical advances in the treatment of retinal diseases have been made. However, some mechanically based limitations of vitreoretinal surgery may result in incomplete removal of the vitreous, especially at the vitreoretinal interface and at the vitreous base. Here, pharmacology can be of assistance. For instance, enzymes that cleave the vitreoretinal junction without damaging the retina or which induce liquefaction may be applied. Neuroprotective and antiproliferative agents may hold the promise of preserving neuronal function when the retina is detached or when proliferative vitreoretinopathy or proliferative diabetic retinopathy has developed. Earlier intervention is possible and can save visual function before the retinal cytoarchitecture is destroyed. Consequently, pharmacologic vitreolysis will change the current concepts of treating retinal and macular diseases.This volume is the first comprehensive up-date on pharmacology-assisted vitreoretinal surgery. Researchers in the fields of medical and surgical retina as well as retinal specialists and vitreoretinal surgeons in clinics will benefit from this topical summary

Table of contents:

1. Title Pages / Table of Contents / List of Contributors / Preface

2. Objective of Pharmacologic Vitreolysis

3. Vitreous as a Substrate for Vitreolysis

4. Hyaluronidase for Pharmacologic Vitreolysis

5. Microplasmin-Assisted Vitrectomy

6. Pharmacologic Vitreodynamics and Molecular Flux

7. Glial Cell Changes of the Human Retina in Proliferative Vitreoretinopathy

8. Alkylphosphocholines: A New Approach to Inhibit Cell Proliferation in Proliferative Vitreoretinopathy

9. Neuroprotection for Diabetic Retinopathy

10. VEGF Inhibitors and Vitrectomy for Diabetic Vitreoretinopathy

11. Tissue Plasminogen Activator-Assisted Vitrectomy: Surgical Drainage of Submacular Hemorrhage

12. Anti-Angiogenic Therapy in the Management of Retinopathy of Prematurity

13. Author Index

14. Subject Index

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Tags: Arnd Gandorfer, Pharmacology, Vitreoretinal, Surgery, Developments, Ophthalmology, Vol 44