Principles of mass spectrometry applied to biomolecules 1st Edition by Chava Lifshitz,Julia Laskin ISBN 0471721840 9780471721840

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Product details:

ISBN 10: 0471721840

ISBN 13: 9780471721840 

Author: Chava Lifshitz, Julia Laskin

An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques.

Table of contents:

CHAPTER 1 Spectroscopy of Neutral Peptides in the Gas Phase: Structure, Reactivity, Microsolvation, Molecular Recognition
CHAPTER 2 Probing the Electronic Structure of Fe–S Clusters: Ubiquitous Electron Transfer Centers in Metalloproteins Using Anion Photoelectron Spectroscopy in the Gas Phase
CHAPTER 3 Ion–Molecule Reactions and H/D Exchange for Structural Characterization of Biomolecules
CHAPTER 4 Understanding Protein Interactions and Their Representation in the Gas Phase of the Mass Spectrometer
CHAPTER 5 Protein Structure and Folding in the Gas Phase: Ubiquitin and Cytochrome c
CHAPTER 6 Dynamical Simulations of Photoionization of Small Biological Molecules
CHAPTER 7 Intramolecular Vibrational Energy Redistribution and Ergodicity of Biomolecular Dissociation
CHAPTER 8 Peptide Fragmentation Overview
CHAPTER 9 Peptide Radical Cations
CHAPTER 10 Photodissociation of Biomolecule Ions: Progress, Possibilities, and Perspectives Coming from Small-Ion Models
CHAPTER 11 Chemical Dynamics Simulations of Energy Transfer and Unimolecular Decomposition in Collision-Induced Dissociation (CID) and Surface-Induced Dissociation (SID)
CHAPTER 12 Ion Soft Landing: Instrumentation, Phenomena, and Applications
CHAPTER 13 Electron Capture Dissociation and Other Ion–Electron Fragmentation Reactions
CHAPTER 14 Biomolecule Ion–Ion Reactions
CHAPTER 15 Thermochemistry Studies of Biomolecules
CHAPTER 16 Energy and Entropy Effects in Gas-Phase Dissociation of Peptides and Proteins

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