Principles of Tumors A Translational Approach to Foundations 2nd Edition by Leon P Bignold ISBN 0128169206 9780128169209
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Product details:
ISBN 10: 0128169206
ISBN 13: 9780128169209
Author: Leon P. Bignold
Principles of Tumors: A Translational Approach to Foundations, Second Edition, provides a concise summary of translational/interdisciplinary topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morphological abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology.
This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine.
Table of contents:
Cover Image
Title Page
Table of Contents
Copyright
Preface to the Second Edition
Chapter 1. Introduction
Chapter 2. Theories and Definitions of Tumors
Chapter 3. Etiopathogenesis of Tumors
Chapter 4. Growth of Cells, Growth Factors, and Oncogenes
Chapter 5. Hereditary Predispositions to Tumors, Tumor Suppressor Genes, and Their Clinico-Genomic Complexities
Chapter 6. The Tumor Types: The Complexities in the Combinations and Variabilities of Their Traits
Chapter 7. Epidemiology of Tumors
Chapter 8. Prevention of Tumors
Chapter 9. Clinical Features of Tumors
Chapter 10. Typing, Grading, and Staging of Cases of Tumor
Chapter 11. Endoscopic Visualization and Imaging Assessments of Cases of Tumor
Chapter 12. Principles of Surgery for Tumors
Chapter 13. Principles of Nonsurgical Therapies
Chapter 14. Aspects of Radiation Therapy
Chapter 15. Specific Aspects of Cytotoxic and Hormonal Drug Therapies
Chapter 16. Immunotherapies
Chapter 17. Gene Therapies Not Related to Immunological Therapies
Chapter 18. Less Common and Controversial Therapies
Chapter 19. Care After Primary Therapy
Chapter 20. Costs, Ethics, and Malpractice Litigation
Appendix 1. Principles of Normal Embryology, Histology, and Related Cell Biology
Appendix 2. Aspects of the Normal Genome
Appendix 3. Fixed Genomic Events and Possible Mechanisms of Their Causation by Etiological Agents
Appendix 4. Genomic Instabilities: Kind, Effects, and Roles in the Immortality of Tumor Cell Populations
Appendix 5. Methods in Histologic and Molecular Assessments of Tumors
Appendix 6. “Biomarkers” in Molecular Pathology and Oncology
Appendix 7. Sublethal Injuries and Deaths of Cells and Tissues
Appendix 8. “Pretarget,” “Target,” and Recovery Capacity Defenses of Cells Against Carcinogens and Cytotoxic Agents
Appendix 9. Developing and Testing New Therapies: Clinical Trials
Index
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Tags: Leon P Bignold, Principles of Tumors, Translational Approach, Foundations