Quality in Laboratory Hemostasis and Thrombosis 1st Edition by Steve Kitchen, John Olson, Eric Preston ISBN 140516803X 9781405168038

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Product details:

ISBN 10: 140516803X

ISBN 13: 9781405168038 

Author: Steve Kitchen, John Olson, Eric Preston 

“Over the last decades, major progress has been made in quality assurance of hemostatic laboratory assays. This book will be an indispensable part of every hemostasis laboratory, where, given its hands-on nature, it will rarely sit to get dusty on the shelves.”
—Frits R. Rosendaal, Leiden University Medical Center

The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired hemorrhagic and thrombotic disorders. Its role in the monitoring traditional anticoagulant therapy as well as therapy using new anticoagulants presents new challenges to the laboratory. Quality in Laboratory Hemostasis and Thrombosis not only addresses these important issues, but also covers international guidelines for testing, the development of international standard materials, management of hemostasis testing from the laboratory to the point of care as well as molecular genetic testing.

Designed as a guide for all those working in hemostasis laboratories, this book details a quality program that, when put into place, will help to improve standards in testing. All of the authors are internationally recognised for their work in hemostasis and thrombosis. Using their experience, they provide information on standards, equipment and methods that will guide the development of a quality program to support all activities in the hemostasis laboratory.

Table of contents:

CHAPTER 1: General Quality Planning in the Hemostasis Laboratory
CHAPTER 2: Hemostasis Test Validation, Performance and Reference Intervals
CHAPTER 3: International Standards in Hemostasis
CHAPTER 4: Sample Integrity and Preanalytical Variables
CHAPTER 5: Internal Quality Control in the Hemostasis Laboratory
CHAPTER 6: External Quality Assessment in Hemostasis: Its Importance and Significance
CHAPTER 7: Initial Evaluation of Hemostasis: Reagent and Method Selection
CHAPTER 8: Point-of-Care Testing in Hemostasis
CHAPTER 9: Assay of Factor VIII and Other Clotting Factors
CHAPTER 10: Application of Molecular Genetics to the Investigation of Inherited Bleeding Disorders
CHAPTER 11: Standardization of D-Dimer Testing
CHAPTER 12: Diagnostic Assessment of Platelet Function
CHAPTER 13: Laboratory Evaluation of von Willebrand Disease: Phenotypic Analysis
CHAPTER 14: Laboratory Analysis of von Willebrand Disease: Molecular Analysis
CHAPTER 15: Dilemmas in Heritable Thrombophilia Testing
CHAPTER 16: Evaluation of Antiphospholipid Antibodies
CHAPTER 17: Monitoring Heparin Therapy
CHAPTER 18: Monitoring Oral Anticoagulant Therapy
CHAPTER 19: Monitoring New Anticoagulants
CHAPTER 20: Detecting and Quantifying Functional Inhibitors in Hemostasis

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Tags: Steve Kitchen, John Olson, Eric Preston, Quality, Laboratory, Hemostasis, Thrombosis