The Newborn Brain Neuroscience and Clinical Applications Second Edition by Hugo Lagercrantz, Hanson 9780521889759 0521889758

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Product details:

ISBN 10: 0521889758
ISBN 13: 9780521889759 
Author: Hugo Lagercrantz, M. A. Hanson, Laura R. Ment, Donald M. Peebles

Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child’s future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.

The Newborn Brain Neuroscience and Clinical Applications Second Table of contents:

1. Reflections on the origins of the human brain

Section 1: Making of the brain

• 2 The molecular basis of central nervous system development
  • Historic box 1
• 3 Holoprosencephaly and microcephaly vera: perturbations of proliferation
  • Historic box 2
• 4 Neuronal migration
• 5 The neonatal synaptic big bang
• 6 Neurotrophic factors in brain development
  • Historic box 3
• 7 Neurotransmitters and neuromodulators
  • Historic box 4
• 8 Glial cell biology

Section 2: Sensory systems and behavior

• 9 Development of the somatosensory system
• 10 Principles of endogenous and sensory activity-dependent brain development: the visual system
  • Historic box 5
• 11 Fetal and neonatal development of the auditory system
• 12 Newborn behavior and perception

Section 3: Radiological and neurophysiological investigations

• 13 Imaging the neonatal brain
• 14 Electroencephalography and amplitude-integrated EEG
• 15 Emergence of spontaneous and evoked electroencephalographic activity in the human brain

Section 4: Clinical aspects

• 16 Infection, inflammation, and damage to fetal and perinatal brain
• 17 Hypoxic–ischemic encephalopathy
• 18 Clinical assessment and therapeutic interventions for hypoxic–ischemic encephalopathy in the full-term infant
• 19 Clinical aspects of brain injury in the preterm infant

Section 5: Follow-up

• 20 Injury and recovery in the developing brain
• 21 Development of motor functions in health and disease
• 22 Antenatal glucocorticoids and programming of neuroendocrine function and behavior

Section 6: Consciousness

• 23 On the emergence of consciousness

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