The Unfolded Protein Response and Cellular Stress Part A 1st Edition by P Michael Conn ISBN 0123851165 9780123851161

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Product details:

ISBN 10: 0123851165

ISBN 13: 9780123851161 

Author: P. Michael Conn

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.

Table of contents:

Section I: UPR and Cell Stress in Normal and Diseased Cells

• The Unfolded Protein Response in Mouse Cerebral Cortex

• Immunohistochemical Detection of the Unfolded Protein Response in Atherosclerotic Plaques

• The role of PDI as a survival factor in cardiomyocyte ischemia

• Measurement of the Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals

• Measurement of the unfolded protein response (UPR) in monocytes

• Assessment of Endurance Exercise Training in Hepatic Endoplasmic Reticulum Stress

• Discovery approaches to UPR in athero-susceptible endothelium in vivo

• Assessment of endoplasmic reticulum stress and the unfolded protein response in endothelial cells

• Measuring the impact of cigarette smoke on the UPR

• Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris

• Induction of ER stress response leading to programmed cell death in Trypanosoma brucei

• Measurement of Activation of the Endoplasmic Reticulum Stress Response in Autoimmune Myositis

• Activation of the unfolded protein response in human acute myeloid leukemia

• Modulation of the Unfolded Protein Response by GRP78 in Prostate Cancer

• Endoplasmic Reticulum Stress In Brain Damage

• Methods and Models for Monitoring UPR associated Macrophage Death during Advanced Atherosclerosis

• Detecting Autophagy in Response to ER Stress Signals in Cancer

• The Unfolded Protein Response Induced By Salt Stress in Arabidopsis

• Measurement of ER Stress Response and Inflammation in the Mouse Model of Non-alcoholic Fatty Liver Disease

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Tags: P Michael Conn, Unfolded, Protein, Response, Cellular, Stress